. The diseases of infancy and childhood . Chondrodystrophia Foetalis, or Achondroplasia. A—Infant, aged nine months.B—Child, aged three years. CHONDRODYSTROPHY FETALIS. 251 organs. The parts at the base of the brain, the pons, may extendabove the sella turcica in an upward instead of a forward direction.This is due to the peculiar changes present at the base of the skull.The pituitary body is normal. The thyroid shows no marked changes.The flat bones are normal; but in the bones which are formed fromcartilage, the so-called endochondral ossification is disturbed. Thesebones, such as the sternu
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. The diseases of infancy and childhood . Chondrodystrophia Foetalis, or Achondroplasia. A—Infant, aged nine months.B—Child, aged three years. CHONDRODYSTROPHY FETALIS. 251 organs. The parts at the base of the brain, the pons, may extendabove the sella turcica in an upward instead of a forward direction.This is due to the peculiar changes present at the base of the skull.The pituitary body is normal. The thyroid shows no marked changes.The flat bones are normal; but in the bones which are formed fromcartilage, the so-called endochondral ossification is disturbed. Thesebones, such as the sternum, patella, and costal cartilages, the tarsaland metacarpal bones, show changes. The long bones present endo-chondral disturbances; there is an absence of the long lines of car-tilaginous cells, and at the ossification zone there is a most irregularproliferation of cartilage-cells and ossification. It is thus that thegrowth of the long bones, of the innominata, and of the bones at thebase of the skull are disturbed. The vertebral col