Avanti West Coast, FirstGroup and Trenitalia West Coast Partnership train at Milton Keynes Central, managed by London NorthWestern Railway TOC

Milton Keynes Central railway station serves Milton Keynes and surrounding parts of Bedfordshire, Buckinghamshire and Northamptonshire (England). The station is located on the West Coast Main Line about 50 miles (80 km) northwest of London. The station is served by Avanti West Coast intercity services, and by West Midlands Trains regional services. This is the principal station for the city, one of seven serving the Milton Keynes urban area. Milton Keynes Central, which opened on 17 May 1982, is by far the busiest and most important of these, as well as being the largest in terms of platforms in use, having overtaken Bletchley when platforms 2A and 6 became operational. Milton Keynes Central has a total of seven platforms. Platforms 1 and 3 are the south and northbound slow platforms, while 4 and 6 are the south and northbound fast platforms. Platforms 2 and 5 are reversible, being slow and fast respectively. Platform 2 is used mainly by terminating stopping services from London Euston, whilst platforms 1 and 3 are used by West Midlands Trains services between Euston and Northampton, Birmingham New Street or Crewe. Platforms 4, 5 and 6 are used by Avanti West Coast inter-city express services between London and the West Midlands, north Wales, the north-west or Scotland. Platform 2A is a five-car south-facing bay platform, originally intended for the extension of Marston Vale Line services from Bedford into Milton Keynes Central this proposal no longer appears in plans for East West Rail, being replaced by a planned service to/from Oxford or Aylesbury (see below). Meanwhile, platform 2A is used only by exception when additional platform capacity is needed, such as when there is a service delay. To the north of the station the six lines reduce to four (two slow and two fast) and there is a mile of five-track running to the south before this also reduces back to four.