RF2K970BX–3D image of Phorbol ester skeletal formula - molecular chemical structure of tumor promoter isolated on white background
RFJR09E7–Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCEN–beautiful pink flower of Euphorbia Milii
RF2J7AXCJ–Close-up shot of the beautiful and brightly colored flowers of the Christ Plant (Euphorbia milii), also called the Crown of thorns or Christ thorn.
RFH28G20–Jatropha podagrica, tartogo, Buddha belly plant, bottleplant shrub, gout plant, purging-nut, Guatemalan rhubarb, and goutystalk
RF2JKDN6C–3D image of Mezerein skeletal formula - molecular chemical structure of toxic diterpene ester isolated on white background
RF2BC175A–Phorbol molecular model with atoms
RFW7HRXA–Protein kinase C delta type, an enzyme which serves as a major receptor for phorbol esters, a class of tumor promoters. 3d rendering.
RFJBB015–Physic nut (Jatropha curcas L.), Euphorbiaceae grows in tropical and subtropical regions
RFGGGH21–Jatropha podagrica or tartogo
RMRHN10W–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. Q CO Q 2 4 a: O. 40 80 120 TIME (min) 0 40 80 120 TIME (min) Figure 5. Other kinase C activators, such as TPA. enhance PSPs (A), while compounds that do not activate the kinase, such as 4-alpha phorbol. have little effect (B). The relatively small effect of 4-alpha phorbol is not due to an inability of the preparation to respond to phor- bol esters, because subsequent treatment with 2 fiM DPBA produced a robust increase in transmission. Peak amplitude of PSPs were mea- sured in both experiments and were normalized by divid
RFJR09E8–Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCDF–Euphorbia neriifolia with green and clean leaves
RF2J7AXCM–Close-up shot of the beautiful and brightly colored flowers of the Christ Plant (Euphorbia milii), also called the Crown of thorns or Christ thorn.
RF2BC1767–Phorbol molecular model with atoms
RFW7HRXM–Serine/threonine-protein kinase D2, an enzyme which can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN). 3d rendering.
RF2BR73TA–Physic nut (Jatropha curcas L.), Euphorbiaceae grows in tropical and subtropical regions
RFR6NNGR–phorbol molecular model
RMRHN13W–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. CHj-O-C—(CH^-CH=CH—(C 0 II CH-O-C—CH, OH' DPBA H -"-c* 0 0 Figure 1. Structures of the compounds whose effects on synaptic transmission were examined in this study. These compounds include a variety of phorbol esters and related compounds (left) and the diacyl- glycerol, l-oleoyl-2-acetylglycerol (right). The phorbol ester derivatives are tetradecanoyl phorbol-acetate (TPA), 12-deoxyphorbol, 13-buty- rate 20-acetate (DPBA). 12-deoxyphorbol, 13-isobutyrate (DPB), and the phorbols, 4-« phorbol and 4-0 phorbol. The structu
RFJR09D7–Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCEE–beautiful pink flower of Euphorbia Milii
RFR6NNGK–phorbol molecular model
RMRHKNT4–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 03 07 06 I05 a £0.4 03 20 40 60 80 100 120 [BODIPY phorbol eslerJ(nM) B n-12) .<n=5) 10 20 30 40 50 60 Time (mm). tochondrial fluorescent marker, rhodamine 123 (10 nM), and with BODIPY phorbol ester (Fig. 1C). In zygotes. the rhodamine signal was punctate and was interpreted as being associated with mitochondria. The BODIPY signal appeared coincident with the rhodamine signal and was also associated with other unde- fined intracellular structures. These studies demonstrate that fluorescently labeled phorbol ester can be u
RFJR09D1–Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCD7–Euphorbia neriifolia with green and clean leaves
RMRHMY5M–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 15 30 Time (min) 45 60. 30 Time (min) 45 60 Figure 7. The effects of various agents on the time course of changes in wet weight of Mercenaria ventricles transferred from 1000 mOsm seawater to 500 mOsm SW. Each point is the mean of 10 ventri- cles; error bars are 1 SD. Treatments are indicated as follows: 7a—solid circles = controls, open circles = FMRFamide (10 " A/); 7b—solid cir- cles = 5-hydroxytryptamine (10" A/), open circles = forskolin (I05 A/); 7c—solid circles = phorbol 12.13-diacetate (107 A/), open cir
RFJR09DX–Manchineel apples on sand. Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCG2–beautiful pink flower of Euphorbia Milii
RMRHKNTK–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 366 CELL AND DEVELOPMENTAL BIOLOGY. 03 07 06 I05 a £0.4 03 20 40 60 80 100 120 [BODIPY phorbol eslerJ(nM) B n-12) .<n=5) 10 20 30 40 50 60 Time (mm). Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original work.. Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 187
RFJR09D0–Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCCW–Euphorbia neriifolia with green and clean leaves
RMRHMY56–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. VOLUME REGULATION IN MERCENAR1A 265 10 5- -5- -10 15 30 Time (min) 45 60. -10 15 30 Time (min) 45 60 Figure 8. The effects of various agents on the time course of changes in wet weight ofMercenaria ventricles transferred to isosmotic seawater (1000 mOsm). Each point is the mean of 10 ventricles; error bars are 1 SD. Treatments are indicated as follows: 8a—solid circles = controls; 8b—solid circles = FMRFamide (106 A/), open circles = 5-hydroxytryptamine (106 M): 8c—solid circles = phorbol 12,13- diacetate (1(T7 A/), open c
RFJR09DY–Manchineel apples on sand. Manchineel Tree (Hippomane mancinella) is one of the most dangerous and toxic trees in the world. Martinique / West Indies
RF2DFNCF4–beautiful pink flower of Euphorbia Milii
RMRHN14D–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 148 L. R. OSSES ET AL.. CHj-O-C—(CH^-CH=CH—(C 0 II CH-O-C—CH, OH' DPBA H -"-c* 0 0 Figure 1. Structures of the compounds whose effects on synaptic transmission were examined in this study. These compounds include a variety of phorbol esters and related compounds (left) and the diacyl- glycerol, l-oleoyl-2-acetylglycerol (right). The phorbol ester derivatives are tetradecanoyl phorbol-acetate (TPA), 12-deoxyphorbol, 13-buty- rate 20-acetate (DPBA). 12-deoxyphorbol, 13-isobutyrate (DPB), and the phorbols, 4-« phorbol and
RMRHMY70–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 264 L. E. DEATON 16 14 12 10 8 6-- 4.. 2- 1 0 Cont 5HT FMRF pQD FLRF DMF 4|3 PDA PMA Figure 6. The effects of various agents on the release ot'amino acids from Mercenaria ventricles transferred to isosmotic seawater (1000 mOsm). Each bar represents the mean of live ventricles; error bars are 1 SD. Treatments: Cont = controls; 5HT = 5-hydroxytryptamine (106 A/); FMRF = FMRFamide (10 " A/); pQD = pQDFLRFamide (10'" M): FLRF = FLRFamide (10"" .M): DMF = dimethylformamide (1.4 ml/); 4/3 = 4-beta-phorbol (10
RMRHKKE5–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 0.55- 0.65 n 10 20 30 Incubation time (mm) PMA - catalase control 40 1 I I n LPS + 1 >Jg ml'1 catalase. 0.55- 0.5 Incubation time (min) Figure 4. Reduction of ferricytochrome c by amoebocytes from Actinia equina in vitro. Twenty-five microliters of washed cells in ocean salts (OS; final concentration 1.3 x 10" ml"') was incubated with 25 M' of phorbol myristate acetate (PMA; final concentration 8 ^g ml ') (a) or lipopolysaccharide (LPS; final concentration 1 ^g ml"1) (b), 25 ^1 of OS and 50 ^1 of ferricytoc
RMRHKKFT–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 446 D. M. C. MUTTON AND V.J. SMITH 3 0.66 -i 0.65 - 0.64- 0.63 - 0.62- 0.61 No catalase. i - PMA concentrations ( Mg ml"1) 0.66-1 0.65- 0.64- 0.63 - 0.62- 0.61 - 0.6 -C] 1 mi"1 catalase No catalase ml"1 catalase -•- 8 >;g ml"1 catalase LPS concentration (tig mj"1) Figure 3. Effect of different phorbol mynstate acetate (PMA). lipopolysaecharide (LPS), and catalase concentrations on the reduction of ferricytochrome c by isolated amoebocytes from Actinia equina in vitro. Twenty-five microliters of wa
RMRHN10B–. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 150 L. R. OSSES ET AL Table I Effect* nl vunoiis compounds i»i tni at l he sqiiui xu/nl synapse Compound Concentration "(• Increase in synaptic response DPBA 1 M.I/ 229±58(n = 8) 2nM 321 ± 53(n = 12) DPB 1 ^M 86 ± 9(n = 5) TPA ZnM 298 + 84 (n = 4) 4-/i phorhol tiM 6± I2(n = 10) 4-n phorbol M.I/ l±23(n = 6) OAG 50 pM 20 (n = 1) 1 00 MM 45+ 18 (n = 8) Increases are expressed as mean change in PSPs or PSCs ± S.E.M. unusually slow response to TPA. Still another phorbol ester known to activate PKC, 12-deoxyphorhol, 13-is
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