Zebrafish, Danio rerio, with human cancer. Zebrafish are a powerful tool for studying human cancers. Transgenic techniques have been employed to model

- Image ID: PR6EKP
Zebrafish, Danio rerio, with human cancer. Zebrafish are a powerful tool for studying human cancers. Transgenic techniques have been employed to model
Paulo Oliveira / Alamy Stock Photo
Image ID: PR6EKP
different types of tumors, including leukemia, melanoma, glioblastoma and endocrine tumors. Transplantation of human cancer cells in embryos or adult zebrafish offers the advantage of studying the behavior of human cancer cells in a live organism. Chemical-genetic screens using zebrafish embryos have uncovered novel druggable pathways and new therapeutic strategies, some of which are now tested in clinical trials. Zebrafish has contributed to novel discoveries or approaches to novel therapies for human cancer. France

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