Transactions of the Royal Society of Edinburgh . Fig. 60.—Secretion of bile before and after hydrastin andsodium salicylate. 2 grains of hydrastin in 2 cc. ofrectified spirit, 1 cc. of bile, and 2 cc. of water in-jected into the duodenum at h and h! 20 grains ofsodium salicylate in 10 cc, of water injected into thelower portion of the intestine at s.. Fig. 61.—Secretion of bile before and after hydrastin. 2 grains ofhydrastin in 2 cc. of bile, 1 cc. of rectified spirit, and 6 cc. ofwater injected into the duodenum at h and ti. Necropsy.—Slightly increased redness of duodenal mucous membrane.V

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Transactions of the Royal Society of Edinburgh . Fig. 60.—Secretion of bile before and after hydrastin andsodium salicylate. 2 grains of hydrastin in 2 cc. ofrectified spirit, 1 cc. of bile, and 2 cc. of water in-jected into the duodenum at h and h! 20 grains ofsodium salicylate in 10 cc, of water injected into thelower portion of the intestine at s.. Fig. 61.—Secretion of bile before and after hydrastin. 2 grains ofhydrastin in 2 cc. of bile, 1 cc. of rectified spirit, and 6 cc. ofwater injected into the duodenum at h and ti. Necropsy.—Slightly increased redness of duodenal mucous membrane.Very slight evidence of purgative action. Result of Experiments with Hydrastin.—-It is a hepatic stimulant of consider-able power, and a feeble intestinal stimulant. The fact shown in Table XXXI — VOL. XXIX. PART I. 3 K 218 PROFESSOR RUTHERFORD ON THE that in Experiment 61 a dose relatively larger in proportion to the size of theanimal than in Experiment 60 produced a smaller effect on the liver—seemsonly explicable by the fact that the subject of the former experiment was, asalready stated, in an abnormal condition. Altogether, hydrastin appears to bea substance eminently worthy of the attention of the physician. Table XXXI. Hydrastin. Total Dose in Grains. Grains per Kilogrammeof Body-weight. Secretion of Bile per Kilo-gramme of Body