. The pathology and differential diagnosis of infectious diseases of animals : prepared for students and practitioners of veterinary medicine . Veterinary medicine; Communicable diseases in animals. 116 GLANDERS serrated scars are occasionally found. In addition to the ulcers, a catarrhal inflammation of the mucous membrane is very apt to be present. Diffuse glanders manifests itself as a diffuse catarrh of the mucous membrane of the nasal and neighboring cavities, with superficial ulceration, thrombosis of the veins, inflammatory in- filtration of the submucosa, considerable thickening of the

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. The pathology and differential diagnosis of infectious diseases of animals : prepared for students and practitioners of veterinary medicine . Veterinary medicine; Communicable diseases in animals. 116 GLANDERS serrated scars are occasionally found. In addition to the ulcers, a catarrhal inflammation of the mucous membrane is very apt to be present. Diffuse glanders manifests itself as a diffuse catarrh of the mucous membrane of the nasal and neighboring cavities, with superficial ulceration, thrombosis of the veins, inflammatory in- filtration of the submucosa, considerable thickening of the
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. The pathology and differential diagnosis of infectious diseases of animals : prepared for students and practitioners of veterinary medicine . Veterinary medicine; Communicable diseases in animals. 116 GLANDERS serrated scars are occasionally found. In addition to the ulcers, a catarrhal inflammation of the mucous membrane is very apt to be present. Diffuse glanders manifests itself as a diffuse catarrh of the mucous membrane of the nasal and neighboring cavities, with superficial ulceration, thrombosis of the veins, inflammatory in- filtration of the submucosa, considerable thickening of the mu- cous membrane and the formation of a peculiar, radiating cicatrix. Both the nodular and infiltrated forms are found in the lungs. In the nodular form, the lungs contain nodules* varying in size from a millet seed to a pea. They are gray by transmitted light, glassy and pearl gray by reflected light, and are surrounded by a con- gested or a hemorrhagic ring. The center of the nodule shows a pale. Fig. 13. Glanders ulcers in the trachea (a) perforation, (after joest.) yellow point in consequence of caseation and disintegration of the innermost cells. These nodules are of different sizes, of varying numbers, and of different ages. The formation of a capsule by a con- nective tissue membrane is induced by a reactive inflammation in the tissue surrounding the nodule. The nodules may be of an embohc origin, situated principally in the periphery of the lung, their structure being the same as that of the nodules in the nasal mucosa. Some- times the lung nodules represent lobular pneumonic foci, in which the alveoli are filled with red and white blood corpuscles and with des- *Nocard showed that when glandered horses are treated with mallein, a certain pro- portion of them recover, in which case nodules that are present in the lungs cease to contain living bacteria, a fact he has fully proved by inoculation. On postmortem examination the nodules may be readily felt by passing the h

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