Lectures on localization in diseases of the brain, delivered at the Faculté de médecine, Paris, 1875 . e analogies are considerable, since the same alteration(gray induration) is in both cases located in the same tissue.But there are also variations worthy of notice ; thus, in prim-itive sclerosis the fascicular lesions are necessarily double, that Those cases where the extension of the lesion exceeds its habitual limits, theinvasion, for example, of the anterior gray cornua, which will be considered fartheron, are certainly among the most decisive arguments which can be employed toestablish

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Lectures on localization in diseases of the brain, delivered at the Faculté de médecine, Paris, 1875 . e analogies are considerable, since the same alteration(gray induration) is in both cases located in the same tissue.But there are also variations worthy of notice ; thus, in prim-itive sclerosis the fascicular lesions are necessarily double, that Those cases where the extension of the lesion exceeds its habitual limits, theinvasion, for example, of the anterior gray cornua, which will be considered fartheron, are certainly among the most decisive arguments which can be employed toestablish the irritative nature of the morbid process. SECONDARY DEGENERATION. 127 is, they occupy the lateral fasciculi of both sides simulta-neously, instead of one side only, as is always the case in con-secutive sclerosis, when the lesion from which it arises is uni-lateral. I will also add that it is very much less extendedtransversely, and there is reason to believe, therefore, thatbeyond the cerebro-spinal or pyramidal fibres, which are theonly ones affected in consecutive sclerosis, primitive sclero-. FlG. 40. Fig. 39. , Fig. 39.—Transverse section of the spinal cord in a case of consecutive lateral fas-cicular sclerosis ; from softening of the optico-striated bodies and the internal capsule.(Cervical region.) Fig. 40.—^Transverse section of the spinal cord in a. case of consecutive lateralfascicular sclerosis. (Dorsal region.) sis invades also the spinal fibres of the lateral fasciculus (com-pare Figs. 39, 40, and 41, and Figs. 42, 43, and 44).