Human tumor cells, colored red, growing in zebrafish (Danio rerio) embryo. Scientists inserted human cancer cells into zebrafish embryos and allowed

- Image ID: PR6EJX
Human tumor cells, colored red, growing in zebrafish (Danio rerio) embryo. Scientists inserted human cancer cells into zebrafish embryos and allowed
Paulo Oliveira / Alamy Stock Photo
Image ID: PR6EJX
them to grow for several days. Then added chemotherapy to the fishes’ water and found that some of the tumors shrank and others didn’t. The use of human oncogenes, often in conjunction with fluorescent reporters to aid the monitoring of tumor initiation and progression, and the isolation and in vivo imaging of cancer cells, demonstrated the cross-species ability of oncogenes to transform zebrafish cells. Similar cancer experiments have been made with mice, but the zebrafish approach may be faster and cheaper, making it accessible for more patients. Cancer research. France